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Overview Acute Interstitial Nephritis

Acute Interstitial Nephritis is a common kidney disorder that causes swelling or inflammation in the kidney. The disease is often linked with certain infections, drug therapies or it may be caused by some unknown agent. Acute Interstitial Nephritis, if not treated properly, may lead to complete loss of kidney function and can be life threatening.

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Symptoms

Swelling of the kidneys can lead to a number of symptoms that include: Fever Rash Body ache Feelings of Nausea or vomiting Loss of appetite Fatigue and weakness Problems in sleeping patterns Changes in the urinate quantity Muscle cramps Swelling of the limbs Itching and irritation on the skin High blood pressure


Causes

Acute Interstitial Nephritis may be caused by: Drug Allergies Kidney Infections Deficiency of potassium in the blood. Presence of excessive calcium or uric acid in the blood.


Diagnosis

The doctor diagnoses the disease by conducting a kidney biopsy, which gives information about the inflammation in the kidneys. An analysis of the urine tells about the specialized white blood cells which are visible in allergic reactions. The doctor may even conduct a gallium scan which detects the areas of infection. Complete blood count test Blood urea nitrogen test Blood creatinine test Blood gas test Urine test Kidney Biopsy


Treatments

Ant-inflammatory drugs Anti-inflammatory medicines might be used for reducing the swelling in the kidneys. Restricting the intake of certain drugs Restricting the intake of medicines like antibiotics and proton pump inhibitors that cause Acute Interstitial Nephritis brings quick relief. Limiting salt intake Reducing the intake of salt and fluid in the diet can relieve the inflammation and the high blood pressure.


Prevention

Acute Interstitial Nephritis, in most cases, can’t be prevented. Limiting the use of medicines that lead to this disease help in reducing the risk factors.


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